Osteoarthritis Arthritis
What is osteoarthritis?
-
Osteoarthritis
(pronounced ah-stee-oh-arth-rite-iss) is the most common form
of arthritis.
-
It
is caused by the breakdown of cartilage. Cartilage is
the tough elastic material that covers and protects the ends
of bones. Bits of cartilage may break off and cause
pain and swelling in the joint between bones. This pain
and swelling is called inflammation.
-
Over
time the cartilage may wear away entirely, and the bones will
rub together.
-
Osteoarthritis
can affect any joint but usually affects hips, knees, hands
and spine.
Osteoarthritis
is a disease that affects joints in the body. It can involve any
joint, but usually concerns hands and weight-bearing joints such
as hips, knees, feet and spine.
Cartilage
is the tough elastic material that covers and protects the ends
of bones. In healthy joints cartilage acts as a shock absorber
when you put weight on the joint. The slippery surface of the
cartilage allows the bones to move smoothly. When a joint develops
osteoarthritis the cartilage gradually becomes rough and thin,
and the bone underneath thickens.
Osteoarthritis
is classified as non-inflammatory arthritis. This suggests that
there is no inflammation (swelling), but recent research shows
that this is not true. Although there is usually no swelling in
the early stage of the disease, as the arthritis progresses there
can be inflammation. Bits of cartilage may break off and float
around inside the joint. This disturbs other soft tissues inside
the joint and can cause pain and swelling between bones. The result
is you may have trouble moving the joint.
Over
time as the cartilage wears down, the bones may form bumps on
their ends. These bumps are called spurs. Or, the cartilage may
wear away entirely, and your bones may rub together.
OA
may lead to other problems such as:
•
The muscles that hold the joint in place weaken because they are
not being used.
• Over time, the joint looses its shape and does not work at all.
How common is
osteoarthritis?
- There
are many kinds of arthritis. The most common kind is called
osteoarthritis
(or OA for short).
- It
affects 3,000,000 (1 in 10) Canadians.
- It
affects men and women in equal numbers.
- Most
people develop osteoarthritis after the age of 45, but it
can occur at any age.
What are the
warning signs of osteoarthritis?
- Pain,
stiffness and swelling around a joint that lasts longer than
two weeks.
- The
joints that are usually affected are the hips, knees, feet
and spine. Finger and thumb joints might also be affected.
- If
you are experiencing persistent joint pain, visit your family
doctor.
Symptoms
of OA usually come on slowly, and involve the area around the
joints. If you have joint pain, stiffness, or swelling for more
than two weeks, see your doctor.
Damage
due to OA progresses slowly over time and may result in several
problems. You may have pain, especially when moving a joint. Sometimes,
you may hear a grating sound when the roughened cartilage on the
surface of the bones rubs together. Bumps or swelling may appear,
especially on the fingers and feet. A joint may feel sore and
stiff, and the joint won't move as easily or as far as it once
did. All these changes can make it hard to move around and to
do everyday tasks, such as opening a jar or walking up stairs.
Joints
Affected
OA commonly affects weight-bearing joints such as hips, knees,
feet and spine. However, non-weight bearing joints such as finger
joints and the joint at the base of the thumb may be affected
as well. It usually does not affect other joints, except when
they have been injured or been put under unusual stress.
How
does the doctor diagnose osteoarthritis?
If
you are experiencing persistent joint pain, visit your family
doctor. Describe the pain in detail including where the pain occurs
and when. The x-ray is the most useful test to confirm osteoarthritis.
What causes osteoarthritis?
- The
exact cause is unknown.
- The
chances of getting osteoarthritis seem to increase with age.
- Some
people with osteoarthritis have other family members with
it.
- Being
overweight can increase your risk of getting osteoarthritis.
- Excess
weight puts stress on joints such as hips and knees.
- Injury
to a joint or repeated overuse of it can also damage the cartilage
and lead to osteoarthritis.
- Other
types of arthritis can also damage joints and lead to osteoarthritis.
No one knows for sure
what causes OA, although scientists are well on their way to
understanding the events that lead to the breakdown of cartilage.
Researchers now think that there are several factors that may
increase your risk for getting OA. Key risk factors include:
heredity; excess weight; injury; joint damage from another type
of arthritis.
Heredity
The way your bones fit together may have been passed on to you
from your parents. Sometimes joints don’t fit right or the cushion
between your bones is not normal. You may not have problems
until you are older.
Excess Weight
Excess weight puts extra stress on the weight-bearing joints,
especially the knees and hips. The good news is losing weight,
even just 10 pounds (4.5 kilograms), can help prevent osteoarthritis
in your knees. Even if you have osteoarthritis in your knees,
losing weight can make you feel better. Less body weight means
less stress on your knees.
Joint Injury
If you damaged a joint and it did not heal completely, you may
end up with osteoarthritis in that joint later in life. Certain
occupations may predispose you to osteoarthritis. For example,
people that must work in a squat position over many years may
be more susceptible to osteoarthritis of the knees.
Complications
of Another Type of Arthritis
Sometimes osteoarthritis is caused by damage from a different
kind of joint disease that occurred years before. For example,
people with rheumatoid arthritis can develop osteoarthritis in
those joints in which the rheumatoid inflammation has largely
burnt out.
Wear and Tear?
Osteoarthritis
used to be thought of as the inevitable result of “wear and tear”
on the joints. Research now shows that normal wear does not actually
cause “tear.” Normal activity and exercise is good rather than
bad for joints and does not cause osteoarthritis.
We
do not yet know the causes or the cure for osteoarthritis, but
researchers in Canada and around the world are trying to learn
why cartilage starts to wear away. In fact, The Arthritis Society
funds many leading edge research projects that bring vital new
insights and lead to new and better treatments for osteoarthritis.
For
example, Canadian researchers have identified some of the enzymes
that damage the cartilage in osteoarthritis. Blocking these enzymes
may be one way to slow down the progression of the disease.
What can you
do about osteoarthritis?
- If
your doctor thinks you have osteoarthritis, he or she may
perform a physical examination and order tests such as x-rays.
- Although
there is no cure for osteoarthritis, there are a number of
steps you can take to manage your pain and lead an active
life.
- Learn
as much as you can about this disease. Speaking with
people who are specialists in arthritis care can provide you
with the information you need.
Establishing the correct
diagnosis is very important, because something can be done to
manage most forms of arthritis, and most therapies work best when
started early in the disease.
Your doctor may be able to diagnose OA based on your medical history
and a physical examination. Sometimes, your doctor may order certain
tests to help confirm the diagnosis, to determine how much joint
damage exists, or to distinguish among different types of arthritis.
These tests may include x-rays, blood tests or joint fluid tests.
Although there is no cure for OA, a lot can be done to help manage
the condition. A variety of treatments can help to lessen
pain and stiffness and to make movement easier. Your active
involvement in developing your prescribed treatment plan is essential.
Medicine: Analgesics
- Acetaminophen
is often the first medication chosen to treat osteoarthritis. It
can relieve pain but does not reduce inflammation.
For mild to moderate
osteoarthritis doctors often recommend acetaminophen (Tylenol®,
Panadol®, Exdol®, etc). Acetaminophen is a pain reliever, but
does not reduce inflammation. For this reason it can usually be
safely taken along with most prescription medications. However,
there are daily limits of acetaminophen that you can take, so
be cautious,
particularly with other medications that contain acetaminophen
(for example, it’s found in many cold remedies). A serious overdose
of acetaminophen can cause liver damage.
Medicine: Creams and Gels
- Creams
and gels that are available over-the-counter may provide temporary
pain relief.
Topical creams and gels
that are available over-the-counter may provide temporary pain
relief, but only in the areas where they are applied. These creams
aren’t as effective as anti-inflammatories. Brands available include:
Bengay Arthritis®, Deep Heating Rub Cream®, Minard’s Joint Relief®,
Marathon Deep Heat Rub®, Menthacin®, Extra-Strength Deep Heating®,
and Arthritis Patch. The majority of creams and gels use heat
or cold to distract you from pain.
Medicine: Codeine Preparations
- If
acetaminophen is not doing enough to ease pain, your doctor
may suggest a combination of acetaminophen and codeine.
If
acetaminophen is not doing enough to ease pain, your doctor may
suggest a combination of acetaminophen and codeine. Codeine is
a narcotic that affects the central nervous system, reducing sensitivity
to pain. It is available in combination with acetaminophen in
low doses without a prescription and in higher doses with a prescription.
Some examples of codeine preparations are Tylenol 1, 2 and 3;
Exdol-8, -15, -30; and Atasol-8, -15, -30.
Codeine
may cause constipation, which can be avoided by simple dietary
changes (prune juice, bran cereals etc.) and stool softeners.
Medicine:
Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Nonsteroidal
anti-inflammatory drugs (NSAIDs) are a type of medication
that helps reduce the pain and swelling of the joints and
decrease stiffness. However, they do not prevent further
joint damage.
These
medications can be used to help reduce pain and swelling of the
joints, and decrease stiffness. However, they do not prevent further
joint damage. NSAIDs reduce pain when taken at a low dose, and
relieve inflammation when taken at a higher dose.
You
can purchase NSAIDs such as acetylsalicylic acid, also known as
ASA (Aspirin®, Anacin®, etc.) and ibuprofen (Motrin®, Advil®,
etc.) without a prescription. If you have more severe pain and
swelling, your doctor may prescribe a different kind of NSAID
such as Naprosyn®, Relafen®, Indocid®, Voltaren®, Feldene®, or
Clinoril®. You may need to take NSAIDs for several weeks before
they take effect completely.
Common
side effects of NSAIDs include stomach upset, diarrhea and abdominal
pain. Elderly people, people with high blood pressure, people
with kidney problems, people who have had a previous stomach ulcer,
and people with congestive heart failure or those who have had
a previous heart attack or stroke should talk to their doctor
before taking any NSAID. NSAIDs can also interact with blood thinners
such as warfarin. With the exception of small dose ASA for circulation
problems, two different NSAIDs should not be taken at the same
time.
COX-2
inhibitors (e.g. Celebrex® and Prexige®) are a specific kind of
NSAID that may be prescribed if traditional NSAIDs are hard on
your stomach, or if you have an increased risk for stomach or
duodenalulcers. People who have had a heart attack or stroke or
experienced serious chest pain related to heart disease should
not use NSAIDs or COXIBs. If you are unsure, speak to your doctor
to determine if this type of treatment is right for you.
To
relieve pain, inflammation and minimize gastrointestinal side-effects,
NSAIDs can also be delivered topically (by applying it directly
to the affected area). At the time of publication, Pennsaid® is
the only available prescription NSAID topical solution approved
by Health Canada for OA of the knees specifically.
Medicine:
Corticosteroids
- Cortisone
may be injected into the joint to relieve severe inflammation.
Cortisone is a steroid that reduces inflammation and swelling.
When osteoarthritis
progresses to the point where it’s hard to get around, corticosteroid
injections may be an option to reduce pain and improve mobility.
Cortisone is a steroid that reduces inflammation and swelling.
It is a hormone naturally produced by the body. Corticosteroids
are man-made drugs that closely resemble cortisone. They are steroids
that can be injected into the joints. An injection can provide
almost immediate relief for a tender, swollen and inflamed joint.
However, this treatment can only be used rarely, since corticosteroids
can weaken the cartilage and remove the minerals from (and therefore
weaken) the bone, resulting in further joint weakness.
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